I occasionally find that the labels in data set are annoying especially when this data set is from outside (means someone else create the data set). The labels will cover the variable names when you check the data and therefore you may incorrectly use the label instead of true variable name in programming. And It normally waste me much time to debug.
There is a very easy way to remove all labels in a single step:
* Remove all the labels and formats in data set; proc datasets lib=work memtype=data; modify data_set_name; attrib _all_ label=''; attrib _all_ format=; run;
Hope it also helps you !